Objectives: This study estimated the prevalence, genotype distribution, and the factors associated with oral human papillomavirus HPV in people who use crack-cocaine PWUCC in a remote Brazilian region. Materials and methods: This cross-sectional study used community-based snowball sampling methods for participant recruitment. HPV diagnosis and genotyping were performed by a real-time polymerase chain reaction.
Logistic regression identified the factors independently associated with oral HPV. Results: In total, Several genotypes were identified, some of them with high oncogenic potential. Conclusions: This study identified important epidemiological characteristics of oral HPV infection among PWUCC-a highly marginalized risk population-underlining the high prevalence of oral HPV with oncogenic potential and the urgent need for control and prevention measures, especially vaccination against this virus.
Clinical relevance: It is necessary to understand the prevalence and risk factors of oral HPV in risk populations as people who use crack-cocaine. Abstract Objectives: This study estimated the prevalence, genotype distribution, and the factors associated with oral human papillomavirus HPV in people who use crack-cocaine PWUCC in a remote Brazilian region.
Substances Crack Cocaine.
